Atlas-guided correction of brain histology distortion

Atlas-guided Histology Reconstruction of Mouse Brain

Histology acquisition often introduces tissue distortions that prevent a smooth 3D reconstruction from being built. In this paper, we propose a method of atlas-guided optimization to the piecewise registration scheme we developed previously. It takes the information of several consecutive slices in a neighbourhood into account. In order to achieve an accurate anatomic presentation, we run the m...

Atlas of Descriptive Histology

The Atlas of Descriptive Histology is an extremely comprehensive and well-organized atlas including 612 illustrations covering everything from basic tissue to full organ histology. In a clear, systematic fashion, the authors move from simple tissue structures to complex organ systems, including micrographs of the adult tongue, lip, teeth, eye, ear, and developing teeth. Each chapter is designed...

Elementary Atlas of Histology

Anatomical atlas-guided diffuse optical tomography of brain activation

We describe a neuroimaging protocol that utilizes an anatomical atlas of the human head to guide diffuse optical tomography of human brain activation. The protocol is demonstrated by imaging the hemodynamic response to median-nerve stimulation in three healthy subjects, and comparing the images obtained using a head atlas with the images obtained using the subject-specific head anatomy. The res...

Atlas-Guided Segmentation of Vervet Monkey Brain MRI

The vervet monkey is an important nonhuman primate model that allows the study of isolated environmental factors in a controlled environment. Analysis of monkey MRI often suffers from lower quality images compared with human MRI because clinical equipment is typically used to image the smaller monkey brain and higher spatial resolution is required. This, together with the anatomical differences...